| Name | Life time | Period with Chair | Major area of research |
| Isaac Barrow | 1630-1677 | 1664-1669 | Classics & Mathematics |
| Sir Isaac Newton | 1642-1727 | 1669-1702 | Mathematics & Physics |
| William Whiston | 1667-1752 | 1702-1710 | Mathematics |
| Nicolas Saunderson | 1682-1739 | 1711-1739 | Mathematics |
| John Colson | 1680-1760 | 1739-1760 | Mathematics |
| Edward Waring | 1736-1798 | 1760-1798 | Mathematics |
| Isaac Milner | 1750-1820 | 1798-1820 | Mathematics & Chemistry |
| Robert Woodhouse | 1773-1827 | 1820-1822 | Mathematics |
| Thomas Turton | 1780-1864 | 1822-1826 | Mathematics |
| Sir George Airy | 1801-1892 | 1826-1828 | Astronomy |
| Charles Babbage | 1792-1871 | 1828-1839 | Mathematics & Computing |
| Joshua King | 1798-1857 | 1839-1849 | Mathematics |
| Sir George Stokes | 1819-1903 | 1849-1903 | Physics & Fluid Mechanics |
| Sir Joseph Larmor | 1857-1942 | 1903-1932 | Physics |
| Paul A.M. Dirac | 1902-1984 | 1932-1969 | Physics |
| Sir M. James Lighthill | 1924-1998 | 1969-1980 | Fluid Mechanics |
| Stephen W. Hawking | 1942- | 1980- | Theoretical Physics |